secretory component of IgA

secretory component of IgA
A polypeptide chain of about 60 kD that aids secretion of the IgA; a portion of the IgA receptor on the plasmalemma of the inner side of the epithelial cells lining the gut, which is proteolysed when the IgA receptor complex has travelled through the cell after receptor-mediated endocytosis at the inner face, to the outer (luminal) face.

Dictionary of molecular biology. 2004.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Secretory component — is a component of IgA which consists of a portion of polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis.… …   Wikipedia

  • secretory component — (SC) a 70,000 dalton glycopeptide occurring in secretory IgA; synthesized not by the plasma cell producing the IgA but added while the IgA is crossing the epithelium; it may protect secretory IgA from proteolytic attack after secretion, or it may …   Medical dictionary

  • secretory immunoglobulin A — secretory IgA; the predominant immunoglobulin in secretions (oral, nasal, bronchial, urogenital, and intestinal mucous secretions and tears, saliva, and milk), a dimer containing the J chain and the secretory component (SC) …   Medical dictionary

  • component — An element forming a part of the whole. [L. com pono, pp. positus, to place together] anterior c. of force a force operating to move teeth anteriorly. c. of complement (C) any one of the nine distinct protein units designated C1 through C9. See… …   Medical dictionary

  • Immunoglobulin A — (IgA) is an antibody playing a critical role in mucosal immunity. More IgA is produced in mucosal linings than all other types of antibody combined. [cite journal |author=S Fagarasan and T Honjo |title=Intestinal IgA Synthesis: Regulation of… …   Wikipedia

  • Immunoglobulin — A protein produced by plasma cells and lymphocytes. Immunoglobulins are an essential part of the body s immune system which attach to foreign substances, such as bacteria, and assist in destroying them. Abbreviated Ig. The classes of… …   Medical dictionary

  • Polymeric immunoglobulin receptor — Polymeric immunoglobulin receptor, also known as PIGR, is a human gene.Polymeric immunoglobulin receptor is a Fc receptor which facilitates the secretion of IgA and IgM. PBB Summary section title = summary text = The poly Ig receptor is expressed …   Wikipedia

  • IGJ — Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides, also known as IGJ, is a human gene.cite web | title = Entrez Gene: IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu… …   Wikipedia

  • Saccharomyces boulardii — Scientific classification Kingdom: Fungi Phylum: Ascomycota Subphylum …   Wikipedia

  • Selective immunoglobulin A deficiency — Infobox Disease Name = PAGENAME Caption = The dimeric IgA molecule. 1 H chain, 2 L chain, 3 J chain, 4 secretory component DiseasesDB = 29569 ICD10 = ICD10|D|80|2|d|80 ICD9 = ICD9|279.01 ICDO = OMIM = 137100 MedlinePlus = 001476 eMedicineSubj =… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”